Razin








 
Ebnemasouyeh Razin tablet with fennel oil is helpful for galactagogue and
comparison of fennel oil and mefenamic acid for the treatment herbal drug for primary dysmenorrhea. primary dysmenorrhea shows the essance of fennel oil can be used as a safe and effect (7)

Drug action mechanism:
The major constiteunts, which include the terpenoid anethole ,inhibit spasms in smooth muscles and has been considered to be the active estrogenic agent.such as increase milk secretion ,promote menstruation.(8,9)
The fennel oil increases gastric and saliva secretion of stomach ,thereby Increasing the appetite and promoting digestion.
Licorice extract increases gastric mucin against peptic ulcer and mildly has galactagogue effect.(10,11)

Indications:
1-galactagogue
2-amenorrhea
3-dysmenorrhea
4-for prevention of menopause symptoms
5-infant colic
6-carminative

contraindication:
fennel is not recommended in pregnancy and prolonged use.(12,13)

Precaution:
In infants. Discontinue use if depression, vomiting or sedation appear (14)

Drug interaction:
In rat, absorption ,distribution and elimination of ciprofloxacin are all affected
with oral administration of fennel.(15)


Side effect:
Rare allergic reaction was reported with fennel seed .but there is not evidence for fennel oil.(16)

Formulation:
RAZIN table contains fennel oil and licorice extract, available in various flavors.

Dosage:
2 tablet 3 times per day

packaging:
500mg Tablets boxes of 100’s and 20’s 500